🧠 Proteinopathies of CNS
🧠 Proteinopathies of the Central Nervous System (CNS)
Misfolded or abnormally aggregated proteins → neuronal dysfunction → progressive neurodegeneration.Many spread in a prion-like pattern (templated...
✨ 2026 Diabetes Criteria: What Actually Changed from 2025?
🎯 I. Medical Goals & HbA1c Regulation
Target unchanged: HbA1c <7% remains the benchmark.
New emphasis: Strong focus on Time-in-Range (TIR) as a core indicator.
Holistic approach:...
🧠 Migraine
🌩️ Pathophysiology of Migraine (High-Performance Summary)
Migraine = a complex neurovascular network disorder driven by brain hyperexcitability, trigeminovascular activation, and defective pain modulation.
❄️1. Genetic &...
🧠Resistant CIDP
🧠 Resistant CIDP (Chronic Inflammatory Demyelinating Polyneuropathy)
Definition:Resistance occurs when CIDP fails to respond to standard therapy, relapses rapidly, or progresses despite treatment.
🔹 Definition Criteria
❌...
🛡️ Autoimmune Disorders
🛡️ Autoimmune Disorders Impacting Peripheral Nerves
Autoimmune conditions can target myelin, axon, nodes of Ranvier, or neuromuscular pathways, producing motor and sensory neuropathies.
1️⃣ Guillain-Barré Syndrome...
🧠CIDP(Demyelinating Polyradiculoneuropathy)
🧠 CIDP (Chronic Inflammatory Demyelinating Polyradiculoneuropathy) – Variants & High-Yield
Definition:Chronic, immune-mediated demyelinating neuropathy 🧬, >8 weeks, often relapsing or progressive. Chronic counterpart of AIDP/GBS...
