🧠Autoimmune paranodopathies
Autoimmune Paranodopathies (Paranodal Neuropathies)
Definition:Immune-mediated neuropathies targeting paranodal axo–glial junctions, distinct from CIDP, with different pathophysiology, clinical features, and treatment response.
🔹 1️⃣ Pathophysiology
🧬 Target proteins...
💉External Ventricular Drain (EVD)
💉 External Ventricular Drain (EVD) – Key Points
Definition:A temporary catheter placed into the lateral ventricle to drain cerebrospinal fluid (CSF) 💧 or monitor intracranial...
🧠🔬McDonald Criteria2024
🧠🔬 McDonald Criteria 2024 – High-Yield Summary
Definition:MS diagnosis requires Dissemination in Space (DIS) 🌐) and Dissemination in Time (DIT ⏳), plus exclusion of alternative...
🧠🧬Patho of Neurodegeneration
🧠🧬 Pathogenesis of Neurodegeneration – High-Yield Overview
Definition:Progressive dysfunction and death of neurons due to interacting molecular pathways, leading to cognitive, motor, or behavioral deficits....
⚡Epileptogenesis – High-Yield Overview
⚡ Epileptogenesis – High-Yield Overview
Definition:Biological process by which a normal brain becomes capable of spontaneous, recurrent seizures. Involves molecular, cellular, and network-level changes over...
🦴Cauda Equina Syndrome (CES)
🧠🦴 Cauda Equina Syndrome (CES)
Definition:Severe compression of lumbosacral nerve roots (L2–S5) → motor weakness, sensory loss, bladder/bowel dysfunction. Neurosurgical emergency; delayed treatment may cause...
