asyanadhikary

Definition A group of severe childhood epilepsies where epileptic activity itself causes progressive cognitive, behavioral, or developmental decline Seizures + EEG abnormalities are toxic to the...

🧠 Non-Compressive Myelopathy – High-Yield Overview Spinal cord dysfunction without external mechanical compression. Pathology is intrinsic: inflammatory, vascular, metabolic, toxic, infectious, genetic, or infiltrative. 🔥 1. Inflammatory / Immune-Mediated (Most common...

🧠🩸 Intraventricular Hemorrhage (IVH) in the NeuroICU – Comprehensive Review 📌 I. Introduction IVH = bleeding into the cerebral ventricular system Historically fatal; modern NeuroICU care 💉...

🧠 Lesion: PPRF / Abducens nucleus + ipsilateral MLF 👁️ Ipsilateral eye: no horizontal movement 👁️ Contralateral eye: abducts only (half movement) + nystagmus 🔼🔽 Vertical movement:...

⚗️ 1️⃣ Anticholinergic Medications (MOST IMPORTANT) Mechanism: Block central acetylcholine → impaired attention, memory, processing speedClinical pearl: Chronic use in elderly ↑ dementia risk (dose-dependent)Examples: Antihistamines:...

🧠 Proteinopathies of the Central Nervous System (CNS) Misfolded or abnormally aggregated proteins → neuronal dysfunction → progressive neurodegeneration.Many spread in a prion-like pattern (templated...