Friday, December 12, 2025

Medical

🔷 Epileptic Encephalopathies (EE)

Definition A group of severe childhood epilepsies where epileptic activity itself causes progressive cognitive, behavioral, or developmental decline Seizures + EEG abnormalities are toxic to the brain ⭐ Core Features 👶 Early onset...

🧠Non-Compressive Myelopathy

🧠 Non-Compressive Myelopathy – High-Yield Overview Spinal cord dysfunction without external mechanical compression. Pathology is intrinsic: inflammatory, vascular, metabolic, toxic, infectious, genetic,...

🩸 Intraventricular Hemorrhage (IVH)

🧠🩸 Intraventricular Hemorrhage (IVH) in the NeuroICU – Comprehensive Review 📌 I. Introduction IVH = bleeding into the cerebral ventricular...

👁️ One and a Half Syndrome

🧠 Lesion: PPRF / Abducens nucleus + ipsilateral MLF 👁️ Ipsilateral eye: no horizontal movement 👁️ Contralateral eye: abducts only...

🧠 Drugs Causing Cognitive Impairment

⚗️ 1️⃣ Anticholinergic Medications (MOST IMPORTANT) Mechanism: Block central acetylcholine → impaired attention, memory, processing speedClinical pearl: Chronic use...

🧠CIDP(Demyelinating Polyradiculoneuropathy)

🧠 CIDP (Chronic Inflammatory Demyelinating Polyradiculoneuropathy) – Variants & High-Yield Definition:Chronic, immune-mediated demyelinating neuropathy 🧬, >8 weeks, often relapsing or progressive. Chronic counterpart of AIDP/GBS...

⚡ Motor Neuropathies

⚡ Motor Neuropathies — Complete High-Yield Overview Motor neuropathies cause pure or predominant motor weakness due to disorders of motor axons, occasionally mimicking motor neuron...

🧠🔬McDonald Criteria2024

🧠🔬 McDonald Criteria 2024 – High-Yield Summary Definition:MS diagnosis requires Dissemination in Space (DIS) 🌐) and Dissemination in Time (DIT ⏳), plus exclusion of alternative...

🧠🧬Patho of Neurodegeneration

🧠🧬 Pathogenesis of Neurodegeneration – High-Yield Overview Definition:Progressive dysfunction and death of neurons due to interacting molecular pathways, leading to cognitive, motor, or behavioral deficits....

⚡Epileptogenesis – High-Yield Overview

⚡ Epileptogenesis – High-Yield Overview Definition:Biological process by which a normal brain becomes capable of spontaneous, recurrent seizures. Involves molecular, cellular, and network-level changes over...

 🦴Cauda Equina Syndrome (CES)

🧠🦴 Cauda Equina Syndrome (CES) Definition:Severe compression of lumbosacral nerve roots (L2–S5) → motor weakness, sensory loss, bladder/bowel dysfunction. Neurosurgical emergency; delayed treatment may cause...